Italy is generally pretty safe. There are a few things you need to worry about, like people-wise. You have some run-ins with some creepy men. Don't let people know where you live, don't give your phone number to random people. So just be aware, be careful. There's also a lot of immigrants in Italy. You just need to be aware that sometimes, if you have loose things, your money will get taken. So just be aware of your belongings and where you're at.
If you want to be taken seriously in Italy, do not go with a hair color other than brown or black. But I went and I have red hair and so I got pet on the bus and on the metro a little bit too often and there's or at least like do some sort of hairstyle where it's not like down and people can pull at it and like pet it but there's this one time that there's I felt someone petting my hair and I was about to get off the bus but her nail her like fake acrylic nail got stuck in my hair and I looked back at her and she's like I'm so sorry while her hand was stuck in my hair which was a great opportunity to get to know her but it was really awkward
Don't wear your backpack on your back. There's a lot of pickpockets that are over there and they're good at what they do. Also wear a fanny pack if you need to or wear one of those things that you can put in underneath your shirt with the little string around it.
They use the train system a lot. There's subways, there's buses, and then just walking. If I were you, I would try and walk as much as possible. It's a great form of exercise. Buses, that's usually the most dependable and the most normal way of transportation.
So one tip about Rome is that generally when you go to restaurants you don't have to tip because they usually incorporate a percentage into the bill that covers the extra expenses for waiters and waitresses so that's just a small tip when you go there.